{"id":271,"date":"2025-03-15T05:48:41","date_gmt":"2025-03-15T05:48:41","guid":{"rendered":"https:\/\/blog.adlington.fr\/index.php\/2025\/03\/15\/polygenic-score-wikipedia\/"},"modified":"2025-03-15T05:48:41","modified_gmt":"2025-03-15T05:48:41","slug":"polygenic-score-wikipedia","status":"publish","type":"post","link":"https:\/\/blog.adlington.fr\/index.php\/2025\/03\/15\/polygenic-score-wikipedia\/","title":{"rendered":"Polygenic score &#8211; Wikipedia"},"content":{"rendered":"<blockquote><p>Recent progress in genetics has developed polygenic predictors of complex human traits, including risk for many important complex diseases[10][11] that are typically affected by many genetic variants, each of which confers a small effect on overall risk.[12][13] In a polygenic risk predictor the lifetime (or age-range) risk for the disease is a numerical function captured by the score which depends on the states of thousands of individual genetic variants (i.e., single-nucleotide polymorphisms, or SNPs).<br \/>\n\u2014 Read on <a href=\"https:\/\/en.m.wikipedia.org\/wiki\/Polygenic_score\">en.m.wikipedia.org\/wiki\/Polygenic_score<\/a><\/p>\n<\/blockquote>\n","protected":false},"excerpt":{"rendered":"<p>Recent progress in genetics has developed polygenic predictors of complex human traits, including risk for many important complex diseases[10][11] that are typically affected by many genetic variants, each of which confers a small effect on overall risk.[12][13] In a polygenic risk predictor the lifetime (or age-range) risk for the disease is a numerical function captured [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[1],"tags":[],"class_list":["post-271","post","type-post","status-publish","format-standard","hentry","category-blog"],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/blog.adlington.fr\/index.php\/wp-json\/wp\/v2\/posts\/271","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blog.adlington.fr\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blog.adlington.fr\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blog.adlington.fr\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/blog.adlington.fr\/index.php\/wp-json\/wp\/v2\/comments?post=271"}],"version-history":[{"count":0,"href":"https:\/\/blog.adlington.fr\/index.php\/wp-json\/wp\/v2\/posts\/271\/revisions"}],"wp:attachment":[{"href":"https:\/\/blog.adlington.fr\/index.php\/wp-json\/wp\/v2\/media?parent=271"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blog.adlington.fr\/index.php\/wp-json\/wp\/v2\/categories?post=271"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blog.adlington.fr\/index.php\/wp-json\/wp\/v2\/tags?post=271"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}