{"id":395,"date":"2025-08-08T05:38:26","date_gmt":"2025-08-08T05:38:26","guid":{"rendered":"https:\/\/blog.adlington.fr\/index.php\/2025\/08\/08\/what-can-a-cell-remember-quanta-magazine\/"},"modified":"2025-08-08T05:44:37","modified_gmt":"2025-08-08T05:44:37","slug":"what-can-a-cell-remember-quanta-magazine","status":"publish","type":"post","link":"https:\/\/blog.adlington.fr\/index.php\/2025\/08\/08\/what-can-a-cell-remember-quanta-magazine\/","title":{"rendered":"What Can a Cell Remember? | Quanta Magazine"},"content":{"rendered":"<blockquote><p>If an intracellular mechanism for memory exists in brainless, unicellular organisms, then it\u2019s possible we inherited some form of it, given the advantages it presents. All eukaryotic cells, including our own, trace their evolutionary origins to a free-living ancestor. That legacy echoes in our every cell, yoking our fates to the vast unicellular realm, where creatures such as protozoans navigate threats, seek succor and sense their way from life to death.<\/p>\n<\/blockquote>\n<p><head><meta charset=\"UTF-8\"><\/head><span style=\"caret-color: rgb(26, 26, 26); font-family: Merriweather, Georgia, serif; font-size: 16px; font-style: normal; font-variant-caps: normal; font-weight: 400; letter-spacing: normal; orphans: auto; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: auto; word-spacing: 0px; -webkit-tap-highlight-color: rgba(0, 0, 0, 0); -webkit-text-size-adjust: 100%; -webkit-text-stroke-width: 0px; background-color: rgb(230, 241, 255); text-decoration: none; display: inline !important; float: none\">From the perspective of the cell, or any other living system that shows the spacing effect, spaced information is evidence of a fairly consistent, slow-moving environment: a steady world. Massed information, on the other hand \u2014 a singular burst of chemicals or an all-night cram session \u2014 might represent a fluky event in a more chaotic environment. \u201cIf the world is changing really fast, you should forget things [more easily], because the things that you learned are going to have a shorter shelf life,\u201d Gershman said. \u201cThey\u2019re not going to be as useful later on, because the world will have changed.\u201d These dynamics are as relevant to a cell\u2019s existence as they are to ours.<\/span><\/p>\n<p><head><meta charset=\"UTF-8\"><\/head><span style=\"caret-color: rgb(26, 26, 26); font-family: Merriweather, Georgia, serif; font-size: 16px; font-style: normal; font-variant-caps: normal; font-weight: 400; letter-spacing: normal; orphans: auto; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: auto; word-spacing: 0px; -webkit-tap-highlight-color: rgba(0, 0, 0, 0); -webkit-text-size-adjust: 100%; -webkit-text-stroke-width: 0px; background-color: rgb(230, 241, 255); text-decoration: none; display: inline !important; float: none\">In neuroscience, Kukushkin writes, the most common definition of memory is that it\u2019s what remains after experience to change future behavior. This is a behavioral definition; the only way to measure it is to observe that future behavior. Think of<\/span><span style=\"caret-color: rgb(26, 26, 26); font-family: Merriweather, Georgia, serif; font-size: 16px; font-style: normal; font-variant-caps: normal; font-weight: 400; letter-spacing: normal; orphans: auto; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: auto; word-spacing: 0px; -webkit-tap-highlight-color: rgba(0, 0, 0, 0); -webkit-text-size-adjust: 100%; -webkit-text-stroke-width: 0px; background-color: rgb(230, 241, 255); text-decoration: none; display: inline !important; float: none\"><span class=\"Apple-converted-space\">&nbsp;<\/span><\/span><em style=\"--tw-border-spacing-x: 0; --tw-border-spacing-y: 0; --tw-translate-x: 0; --tw-translate-y: 0; --tw-rotate: 0; --tw-skew-x: 0; --tw-skew-y: 0; --tw-scale-x: 1; --tw-scale-y: 1; --tw-pan-x; --tw-pan-y; --tw-pinch-zoom; --tw-scroll-snap-strictness: proximity; --tw-gradient-from-position; --tw-gradient-via-position; --tw-gradient-to-position; --tw-ordinal; --tw-slashed-zero; --tw-numeric-figure; --tw-numeric-spacing; --tw-numeric-fraction; --tw-ring-inset; --tw-ring-offset-width: 0px; --tw-ring-offset-color: #fff; --tw-ring-color: rgba(59,130,246,.5); --tw-ring-offset-shadow: 0 0 #0000; --tw-ring-shadow: 0 0 #0000; --tw-shadow: 0 0 #0000; --tw-shadow-colored: 0 0 #0000; --tw-blur; --tw-brightness; --tw-contrast; --tw-grayscale; --tw-hue-rotate; --tw-invert; --tw-saturate; --tw-sepia; --tw-drop-shadow; --tw-backdrop-blur; --tw-backdrop-brightness; --tw-backdrop-contrast; --tw-backdrop-grayscale; --tw-backdrop-hue-rotate; --tw-backdrop-invert; --tw-backdrop-opacity; --tw-backdrop-saturate; --tw-backdrop-sepia; --tw-contain-size; --tw-contain-layout; --tw-contain-paint; --tw-contain-style; box-sizing: border-box; border: 0px solid; caret-color: rgb(26, 26, 26); font-family: Merriweather, Georgia, serif; font-size: 16px; font-variant-caps: normal; font-weight: 400; letter-spacing: normal; orphans: auto; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: auto; word-spacing: 0px; -webkit-tap-highlight-color: rgba(0, 0, 0, 0); -webkit-text-size-adjust: 100%; -webkit-text-stroke-width: 0px; text-decoration: none\">S. roeselii<\/em><span style=\"caret-color: rgb(26, 26, 26); font-family: Merriweather, Georgia, serif; font-size: 16px; font-style: normal; font-variant-caps: normal; font-weight: 400; letter-spacing: normal; orphans: auto; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: auto; word-spacing: 0px; -webkit-tap-highlight-color: rgba(0, 0, 0, 0); -webkit-text-size-adjust: 100%; -webkit-text-stroke-width: 0px; background-color: rgb(230, 241, 255); text-decoration: none; display: inline !important; float: none\"><span class=\"Apple-converted-space\">&nbsp;<\/span><\/span><span style=\"caret-color: rgb(26, 26, 26); font-family: Merriweather, Georgia, serif; font-size: 16px; font-style: normal; font-variant-caps: normal; font-weight: 400; letter-spacing: normal; orphans: auto; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: auto; word-spacing: 0px; -webkit-tap-highlight-color: rgba(0, 0, 0, 0); -webkit-text-size-adjust: 100%; -webkit-text-stroke-width: 0px; background-color: rgb(230, 241, 255); text-decoration: none; display: inline !important; float: none\">snapping back into its holdfast, or a lab rat freezing up at the sight of an electrified maze it\u2019s tangled with before. In these cases, how an organism reacts is a clue that prior experience left a lingering trace.<\/span><\/p>\n<p><head><meta charset=\"UTF-8\"><\/head><span style=\"caret-color: rgb(26, 26, 26); font-family: Merriweather, Georgia, serif; font-size: 16px; font-style: normal; font-variant-caps: normal; font-weight: 400; letter-spacing: normal; orphans: auto; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: auto; word-spacing: 0px; -webkit-tap-highlight-color: rgba(0, 0, 0, 0); -webkit-text-size-adjust: 100%; -webkit-text-stroke-width: 0px; background-color: rgb(230, 241, 255); text-decoration: none; display: inline !important; float: none\">Perhaps a definition of memory should extend beyond behavior to encompass more records of the past. A vaccination is a kind of memory. So is a scar, a child, a book. \u201cIf you make a footprint, it\u2019s a memory,\u201d Gershman said. An interpretation of memory as a physical event \u2014 as a mark made on the world, or on the self \u2014 would encompass the biochemical changes that occur within a cell. \u201cBiological systems have evolved to harness those physical processes that retain information and use them for their own purposes,\u201d Gershman said.<\/span><br \/>\n\u2014 Read on <a href=\"https:\/\/www.quantamagazine.org\/what-can-a-cell-remember-20250730\/\">www.quantamagazine.org\/what-can-a-cell-remember-20250730\/<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>If an intracellular mechanism for memory exists in brainless, unicellular organisms, then it\u2019s possible we inherited some form of it, given the advantages it presents. All eukaryotic cells, including our own, trace their evolutionary origins to a free-living ancestor. That legacy echoes in our every cell, yoking our fates to the vast unicellular realm, where [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[1],"tags":[],"class_list":["post-395","post","type-post","status-publish","format-standard","hentry","category-blog"],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/blog.adlington.fr\/index.php\/wp-json\/wp\/v2\/posts\/395","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blog.adlington.fr\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blog.adlington.fr\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blog.adlington.fr\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/blog.adlington.fr\/index.php\/wp-json\/wp\/v2\/comments?post=395"}],"version-history":[{"count":1,"href":"https:\/\/blog.adlington.fr\/index.php\/wp-json\/wp\/v2\/posts\/395\/revisions"}],"predecessor-version":[{"id":396,"href":"https:\/\/blog.adlington.fr\/index.php\/wp-json\/wp\/v2\/posts\/395\/revisions\/396"}],"wp:attachment":[{"href":"https:\/\/blog.adlington.fr\/index.php\/wp-json\/wp\/v2\/media?parent=395"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blog.adlington.fr\/index.php\/wp-json\/wp\/v2\/categories?post=395"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blog.adlington.fr\/index.php\/wp-json\/wp\/v2\/tags?post=395"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}